B-LYMPHOCYTE NATURE OF HAIRY CELLS IN HAIRY-CELL LEUKÆMIA
نویسندگان
چکیده
منابع مشابه
Hairy cell leukemia: B-lymphocyte and phagocytic properties.
The diagnosis of hairy cell leukemia was made in three patients by phase-contrast microscopy and histochemistry of the abnormal peripheral blood cells. Both IgM and IgD surface immunoglobulins were resynthesized after these cells were trypsinized and cultured. Aggregate or Fc receptors were demonstrated on hairy cells. The ability to phagocytose latex was also a property of hairy cells; however...
متن کاملProduction of B cell growth factor(s) by neoplastic B cells from hairy cell leukemia patients.
Recent studies have shown that normal human T cells contain a high-molecular-weight (mol wt) protein exhibiting B cell growth factor (BCGF) activity. Other studies have shown that virally transformed human B cells also secrete a high-mol-wt BCGF-like molecule in vitro. We have studied neoplastic B cells from patients with untreated hairy cell leukemia (HCL) to ascertain whether such cytoplasmic...
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Hairy cell leukaemia is a rare form of lymphoproliferative disease that affects 2% of leukaemia patients and was first described in 1958 as leukaemic reticuloendotheliosis. The typical presentation is pancytopenia, splenomegaly and abnormal lymphoid cells in blood with hairy cytoplasmic projections. The pathological hairy cell resembles in many ways B-lymphocyte as in chronic lymphocytic leukae...
متن کاملHairy cell leukemia-variant.
Hairy cell leukaemia variant is a very rare chronic lymphoproliferative disorder and is closely related to hairy cell leukemia. We hereby describe a case of hairy cell leukaemia variant for the first time in Saudi Arabia. An elderly Saudi man presented with pallor, massive splenomegaly, and moderate hepatomegaly. Hemoglobin was 7.7 g/dl, Platelets were 134 x109/l and white blood count was 140x1...
متن کاملHairy cell sarcoma.
A 39-year-old coal merchant presented to his family practitioner with a seven month history of swelling of the left side of his face. He was referred to hospital where a left parotid mass was noted. All routine haematological and biochemical investigations were normal. A needle biopsy of the parotid mass, showed, on light microscopy using mercury based fixation, the presence of cells whose appe...
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ژورنال
عنوان ژورنال: The Lancet
سال: 1974
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(74)91970-9